- Heterotopic bone formation in normal gastric cardiac mucosa.
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Seok Hyeon Eom, Chang Hwan Park, Duk Won Chung, Sang Hyeok Lee, Ji Young Seo, Yeong Sung Kim, Dong Hyup Kwak, Jung Hee Kim
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Yeungnam Univ J Med. 2016;33(2):146-149. Published online December 31, 2016
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DOI: https://doi.org/10.12701/yujm.2016.33.2.146
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- Heterotopic bone formation in the gastrointestinal tract is a rare phenomenon. Most reported cases were associated with benign and malignant neoplasms, except for a case in which heterotopic bone formation was found in a patient with Barrett's esophagus. The exact pathogenesis of the disease has not yet been established. However, most heterotopic bones found in the gastrointestinal tract were associated with mucinproducing tumors of the appendix, colon, and rectum. Inflammation may also play a role in osseous metaplasia in a case with bone formation at the base of an ulcer in Barrett's esophagus. Here, we report on a patient with heterotopic bone formation in normal gastric cardiac mucosa. A 50-year-old female visited our hospital for a routine health examination. She had no gastrointestinal symptoms, and her physical examination, blood test, X-ray, urine, and stool examination results were normal. A 0.3 cm sized polypoid lesion located just below the squamocolumnar junction was observed on upper gastrointestinal endoscopy. A piece of biopsy was taken. Histologically, a lamella bone trabecula and chronic inflammatory cells were observed in the gastric cardiac mucosa. The follow-up endoscopy performed one month later showed no residual lesion.
- Choledochocele containing a stone mistaken as a distal common bile duct stone.
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Tae Young Kwak, Chang Hwan Park, Seok Hyeon Eom, Hong Suk Hwang, Duk Won Chung, Ji Young Seo, Yeong Sung Kim, Dong Hyup Kwak
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Yeungnam Univ J Med. 2015;32(1):60-64. Published online June 30, 2015
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DOI: https://doi.org/10.12701/yujm.2015.32.1.60
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- A choledochocele is an expanded sac of the duodenal side of the distal common bile duct (CBD), and is categorized as a type III choledochal cyst. Unlike other choledochal cysts, it can be easily overlooked because of its very low prevalence, non-specific clinical symptoms, and lack of distinctive radiological findings. However, a patient having a repeated pancreaticobiliary disorder with an unknown origin, frequent abdominal pain after cholecystectomy, or repeated non-specific gastrointestinal symptoms can be suspected as having a choledochocele, and a more accurate diagnosis can be achieved via endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound. Because it rarely becomes malignant, a choledochocele can be treated via endoscopic sphincterotomy (EST) and surgical treatment. The authors were able to diagnose choledochocele accompanied by a stone in a patient admitted to the authors' hospital due to cholangitis and pancreatitis. The patient's condition was suspected to have been caused by a distal CBD stone detected via multiple detector computed tomography and ERCP, and was successfully treated via EST.
- A Case of Aggravated Hyperplastic Gastric Polyps after Treatment with Long-term Proton Pump Inhibitors.
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Ho Tae Kim, Jong Wan Park, Seok Hyeon Eom, Tae Yeung Kwak, Hong Suk Hwang, Yeung Sung Kim, Dong Hyup Kwak, Jung Hee Kim
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Yeungnam Univ J Med. 2013;30(2):141-144. Published online December 31, 2013
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DOI: https://doi.org/10.12701/yujm.2013.30.2.141
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- Hyperplastic gastric polyps (HPPs) are the most common type of gastric polyps. They are assumed to be caused by chronic inflammation and regenerative proliferation, although this has not been clearly investigated yet. Many studies suggested the development of fundic gland polyps and carcinoid during long-term proton pump inhibitor (PPI) therapy, but the relationship between PPIs and HPPs is still unclear. We encountered a patient who showed aggravation of HPPs after long-term use of PPIs. A 58-year-old male patient with liver cirrhosis visited our hospital because of hematemesis. We started PPI medication after confirming esophageal variceal bleeding and duodenal ulcer with blood clot in its base via emergency endoscopy. He took PPIs for three years because of an intractable duodenal ulcer. There was a marked increase in the size of the pre-existing polyps and in the development of new polyps. We presumed that the PPIs caused the aggravation of the HPPs, so we stopped their administration. After five months, the HPPs shrank and the polyps were partially degraded. More prospective studies are needed to investigate the relationship between HPPs and PPIs.
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Citations
Citations to this article as recorded by  - Spontaneous Regression of Hyperplastic Gastric Polyps
Soo Yong Choi, Jong Kyu Park, Sang Jin Lee, Woo Jin Jung, Hak Soo Kim, Gab Jin Cheon, Dae Woon Eom
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2017; 17(4): 213. CrossRef
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